Diamond ‘spin-off’ tech could lead to low-cost medical imaging and drug discovery tools

1 year ago Lawrence Berkeley National Laboratory 0
It may sound contradictory, but diamonds are the key to a new technique that could provide a very-low-cost alternative to multimillion-dollar medical imaging and drug-discovery devices. An international team led by scientists at the Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) and UC Berkeley discovered how to exploit defects in nanoscale and microscale diamonds and Read More

Researchers discover how body temperature wrecks potential dengue, Zika vaccin

1 year ago University of North Carolina Health Care 0
A major route toward creating effective vaccines against dengue virus and Zika involves the E protein that covers the surface of each viral particle. If we could develop strong antibodies against this E protein, then that would be the crux of a formidable vaccine—based on the important fact that the 180 E proteins come in Read More

How the gut influences neurologic disease

1 year ago Brigham and Women's Hospital 0
A study published this week in Nature sheds new light on the connection between the gut and the brain, untangling the complex interplay that allows the byproducts of microorganisms living in the gut to influence the progression of neurodegenerative diseases. Investigators from Brigham and Women’s Hospital (BWH) have been using both animal models and human Read More

Researchers find new way to stimulate cellular recycling process

1 year ago Brown University 0
Brown University researchers studying the biology of aging have demonstrated a new strategy for stimulating autophagy, the process by which cells rebuild themselves by recycling their own worn-out parts. In a study published in the journal Cell Reports, the researchers show that the approach increased the lifespans of worms and flies, and experiments in human Read More

Multi-Drug Resistant Infections Rising in Children

1 year ago Rush University Medical Center 0
Antibiotic-resistant Acinetobacter baumannii infections, one of the most common hospital-acquired infections in children across the United States, are on the rise, according to results of a recent study published in the Journal of the Pediatric Infectious Diseases Society on March 22. “Acinetobacter are bacteria known to cause serious infections and notoriously difficult to treat because Read More

Researchers Uncover Another Tool to Fight Superbugs

1 year ago Kenny Walter | 0
The growing threat of antibiotic resistant bacteria has led researchers around the globe to look at ways to stop these ‘superbugs’. Researchers from McGill University in Montreal have presented in detail how specific bacterial enzymes called kinases, confer resistance to macrolide antibiotics—a widely used class of antibiotics and an alternative medication for patients with penicillin Read More

AACR 2018: Dual Inhibition of IDO1 and PD-L1 Safe in Patients With Advanced Solid Tumors

1 year ago American Association for Cancer Research 0
An immunotherapy treatment combining the IDO1 inhibitor epacadostat and the PD-L1 inhibitor durvalumab was found to be safe in patients with advanced solid tumors, with safety data similar to treatment with durvalumab alone, according to data presented from the ongoing ECHO-203 clinical trial at the AACR Annual Meeting 2018, April 14-18, in Chicago.   “Immune Read More

A new point-of-need nanodiagnostic for better healthcare

1 year ago CORDIS 0
The Nano4 project takes fast, reliable and low-cost molecular point of care (POC) diagnostic tools down to the nano-scale, offering better healthcare outcomes for patients. Medics working in migratory hotspots, in countries with low laboratory infrastructure or in other demanding situations often need to be able to screen large populations quickly, in a non-centralised manner. Read More

Molecular Movies of RNA Guide Drug Discovery

1 year ago Duke University 0
Thumb through any old science textbook, and you’ll likely find RNA described as little more than a means to an end, a kind of molecular scratch paper used to construct the proteins encoded in DNA. But over the last decade, scientists have begun to see RNA as an end in itself. Research programs and biotech Read More